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Tacalyx appoints Jean Engela as Chief Executive Officer to spearhead next phase of growth

The former CEO of ADC company NBE Therapeutics takes over from co-founder Dr. Peter Sondermann, who continues as Chief Scientific Officer.

Jean Engela, CEO, next to a quote on leading Tacalyx toward becoming a clinical-stage biotech company

Tacalyx has appointed Jean Engela as Chief Executive Officer. Co-founder and former CEO Dr. Peter Sondermann continues at Tacalyx as Chief Scientific Officer and focuses on the R&D strategy.

Jean Engela brings more than two decades of experience in drug research and development. As CEO and board member of the ADC company NBE Therapeutics, Jean Engela led its development from a start-up into a biotech with a diversified ADC pipeline. Before that he was Executive Drug Development Leader at Boehringer Ingelheim, responsible for the global development of oncology and immunology programmes, including small molecules, monoclonal antibodies, multi-specific antibodies and T-cell engagers, and led the integration of NBE Therapeutics into Boehringer Ingelheim's R&D organization.

"It is a great pleasure to lead Tacalyx as we gain momentum and advance toward becoming a clinical-stage biotech company. […] In the coming months, we look forward to navigating key value inflection points as IND-enabling studies for our lead programme get underway."

— Jean Engela, CEO

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AACR 2026 poster 5631 on TCX-201, with in vitro, in vivo, pharmacokinetic and toxicology panels

Scientific presentations

TCX-201 and TCX-101 data presented at AACR 2026

Two posters at the AACR Annual Meeting 2026 in San Diego: the preclinical profile of first clinical candidate TCX-201 (Poster 5631) and TCX-101 as a trispecific T-cell engager (Poster 5584).